The Mouse Anti-TRXR1/TXNRD1 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to thioredoxin reductase 1, and TXNRD1. This antibody recognizes Human antigen. The Mouse Anti-TRXR1/TXNRD1 Antibody has been validated for the following applications: Cell Sorting, Isolation, Flow Cytometry, Immunocytochemistry, and Immunofluorescence.
Description
Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor the development of Drug-induced liver injury (DILI), which is the most common adverse drug reaction